‹ ›
MYP_006242
← PREVIOUS NEXT → BACK
Basic Information
Rubiscolin-6 opioid
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/antinociceptive activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Regulatory peptide ▸ Biological regulation
Standard
6 amino acids
C39H54N6O10
Standard
Sequence
YPLDLF
Physicochemical Analysis
766.88 Da
4.05
-1.24
-1.44
-0.2066
0.67
0.40
0.47
28.90
130.00
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
257.56
1.09
8.0
9.0
20.0
55.0
3.0
5.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0257214 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
24.4 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0274719 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Rubiscolin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
24.4
IC50
PaperWang W., Gonzalez de Mejia E.. A new frontier in soy bioactive peptides that may prevent age-related chronic diseases. Comp. Rev. Food Sci. Food Safety, 2005, 4, 63 -77.
RECORD: Rec_0311263 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Soymorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperStefanucci A., Dimmito M. P., Tenore G., Pieretti S., Minosi P., Zengin G. et al.. Plant-derived peptides rubiscolin-6, soymorphin-6 and their C-terminal amide derivatives: Pharmacokinetic properties and biological activity. J. Funct. Foods, 73, 104154, 2020.
RECORD: Rec_0316377 VERIFIED: NO
Provenance & Taxonomy
Glycine max [Plant]; Fabaceae [Plant]
3847; 3803
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0384773 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Rubiscolin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Regulatory
PaperKaneko K., Mizushige T., Miyazaki Y., Lazarus M., Urade Y., Yoshikawa M., Kanamoto R., Ohinata K.. ¦Ä-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice. Am. J. Physiol. Regul. Integr. Comp. Physiol., 306, R265-R272, 2014.
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3