Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC112H164N28O36S

DescriptionStandard

        GTNGKPPDPKKESQDYLGWMDF
    

Molecular Weight2510.73 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0563

GRAVY Index-1.54

Hydrophobic Moment 0.30

Boman Index-0.18

Instability Index29.27

Aliphatic Index 17.73

Aromaticity 0.1364

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1037.97

LogP -10.10

H-bond Donors 33.0

H-bond Acceptors 36.0

Rotatable Bonds 79.0

Heavy Atoms 177.0

Ring Count 7.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044973 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0069752 VERIFIED: NO

Provenance & Taxonomy

OrganismVaranus varius [Animal]

FamilyGastrin/cholecystokinin

Tax ID8559

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsTyr16 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0382565 VERIFIED: NO

Provenance & Taxonomy

OrganismVaranus varius [Animal]

FamilyCholecystoxin

Tax ID8559

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods16:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour