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MYP_006185
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C34H45N5O8
Standard
Sequence
LPYPY
Physicochemical Analysis
651.75 Da
5.52
-0.24
-0.45
-0.0484
-0.40
0.21
0.36
71.20
78.00
0.4000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
202.60
1.29
6.0
8.0
13.0
47.0
4.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010119 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
28.9
IC50
PaperGomez-Ruiz J. A., Ramos M., Recio I.. Identification of novel angiotensin-converting enzyme-inhibitory peptides from ovine milk proteins by CE-MS and chromatographic techniques. Electrophoresis, 28, 4202-4211.
RECORD: Rec_0011078 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0012880 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]; Bos taurus [Animal]
9940; 9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0034715 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Casein-derived peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
28.9 μM
IC50
RECORD: Rec_0099209 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
ACE-inhibitory peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
28.9 μM
IC50
PaperIdentification of novel angiotensin-converting enzyme-inhibitory peptides from ovine milk proteins by CE-MS and chromatographic techniques. PMID17948260 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17948260/
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