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MYP_006173
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
5 amino acids
C32H46N8O8
Standard
Sequence
RYLGY
Physicochemical Analysis
670.76 Da
8.59
0.76
0.55
0.1516
-0.74
0.63
-0.09
-24.06
78.00
0.4000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
282.08
-0.83
11.0
9.0
19.0
48.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0234596 VERIFIED: NO
Provenance & Taxonomy
Bovine alphas [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Multifunctional ACE inhibitory Antioxidant Hypotensive
0.71 μM
IC50
RECORD: Rec_0247922 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Macrophage-modulating
Caco-2 cells
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0296688 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
0.71 μM
IC50
PaperNovel casein-derived peptides with antihypertensive activity | Contreras, M. del Mar. et al. | DOI: 10.1016/j.idairyj.2009.05.004 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0351488 VERIFIED: YES
Provenance & Taxonomy
Brassica napus [Plant]
ACE-inhibitory peptide
3708
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperGlycinyl-Histidinyl-Serine (GHS), a Novel Rapeseed Protein-Derived Peptide Has Blood Pressure-Lowering Effect in Spontaneously Hypertensive Rats PMID23919612 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23919612/
RECORD: Rec_0364905 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Mucin secretagogue
HT29-MTX cells
Mucin secretion assay
PaperFood-Derived Peptides Stimulate Mucin Secretion and Gene Expression in Intestinal Cells | Martinez-Maqueda, D. et al. | DOI: 10.1021/jf301279k Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
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