Peptide Database

Peptide NameMela 6

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC131H205N33O41S6

DescriptionStandard

        GIPTCGETCFKGKCYTPGCSCSYPICKKD
    

Molecular Weight3090.62 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0587

GRAVY Index-0.29

Hydrophobic Moment 0.42

Boman Index0.01

Instability Index4.67

Aliphatic Index 26.90

Aromaticity 0.1034

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1172.04

LogP -14.19

H-bond Donors 46.0

H-bond Acceptors 49.0

Rotatable Bonds 96.0

Heavy Atoms 211.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212362 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus latifolius [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Anticancer Cytotoxic