Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length445 amino acids

Chemical FormulaC2181H3440N566O633S15

DescriptionStandard

        MWLIAVVLMTLSLASLGAPSTHVATEPGIRVALTQEGLNKVSHDLTGWFQERISSIHPPGINGTVPVWIGAVRYFLTDMSVVRCDLPEPQVSYADGQGITVVLDGLSMHISGKWRAKLSFLSTGGTFDLAIFNVQVKATLKLGSDKEGHLSVTTGPCVASAEKICSTLDIGVQELDRNLTALPVQLPVGRYVFVAIPLTNPPTVKGSHAQIDAKGAFYSRKNATEPPFSPDHFNLTVGRNRMIYFGASEFCVNTATFAYFTGGLLQINITDDMIPAQSPIQLNTSDFGELIPELPRQFPNELMTVRLRASQSPRFSLQANLWTLDMWLSADTFAIQPNSTLAPLFTLDLNVTFSGKALISDGLLKGSMKLSNVSVSLGSSHIGPFSINPLQVAVNNLFTDVLLPQLNKLLQVGFKMPTVFGYSMVNAQLTIDNGFVSVSTDILIK
    

Molecular Weight48199.03 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-2.81

Net Charge (pH 7.4) -3.56

Charge Density (pH 7.0) -0.0063

GRAVY Index0.21

Hydrophobic Moment 0.70

Boman Index0.18

Instability Index35.89

Aliphatic Index 100.97

Aromaticity 0.0831

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 43680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0098943 VERIFIED: NO

Provenance & Taxonomy

OrganismChanos chanos (Milkfish) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria