Peptide Database

Peptide NameAlpha-defensin 22

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC448H733N137O142S7

DescriptionStandard

        MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR
    

Molecular Weight10534.90 Da

Isoelectric Point (pI)6.56

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.48

Hydrophobic Moment 0.70

Boman Index-0.16

Instability Index64.57

Aliphatic Index 80.75

Aromaticity 0.0538

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4575.59

LogP -51.56

H-bond Donors 166.0

H-bond Acceptors 150.0

Rotatable Bonds 359.0

Heavy Atoms 734.0

Ring Count 9.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014607 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal