Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC513H785N143O149S9

DescriptionStandard

        MLKFISLGLLIVALCFFGGIMSFPAEFEQAQSEENFEPADVLPFSENEPQENEHHRFRRATCDLLSISTPWGSVNHAACAAHCLALNRGFRGGYCSSKAVCTCRK
    

Molecular Weight11628.17 Da

Isoelectric Point (pI)6.04

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.74

Charge Density (pH 7.0) -0.0209

GRAVY Index-0.01

Hydrophobic Moment 0.62

Boman Index0.08

Instability Index54.11

Aliphatic Index 73.52

Aromaticity 0.1048

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4643.75

LogP -47.06

H-bond Donors 166.0

H-bond Acceptors 160.0

Rotatable Bonds 377.0

Heavy Atoms 814.0

Ring Count 21.0

Amide Bonds 112.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127517 VERIFIED: NO

Provenance & Taxonomy

OrganismSimulium bannaense [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence