Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length286 amino acids

Chemical FormulaC1464H2279N371O406S15

DescriptionStandard

        MENVCERVTNSVSSELQPYFQTLPVMTKIDAVAGINYGLVAPPTTTAETLDVQMKGEFYSQNHHNPPPFAPPVMEFPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLRDDMIPKESKFRLTTKFFGNFLPEVAKRFPNMKIQIHVSASTPPHLSVQPTGLTFYPAVDVQAFAVLPNSSLASLFLIGMHTTGSMEVSTKSDRLVGEVKLNRLLLELKHSDIGPFPVELLQDIMNYMVPILVLPRVNEKLQKGFPLPMPARVQLYNMVLQPHHNFLLFGADVVYK
    

Molecular Weight32053.97 Da

Isoelectric Point (pI)6.50

Net Charge (pH 7.0)-1.70

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.0059

GRAVY Index0.02

Hydrophobic Moment 0.66

Boman Index0.14

Instability Index41.75

Aliphatic Index 91.61

Aromaticity 0.0979

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 14900.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305460 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Bacterium]

FamilyBPI

Tax ID61853

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence