Peptide Database

Peptide NameMelittin-N (MEL-N), (MLT)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC351H553N85O99S2

DescriptionStandard

        MKFLVNVALVFMVVYISYIYAAPEPEPAPEPEAEADAEADPEAGIGAVLKVLTTGLPALINWIKRKRQQG
    

Molecular Weight7611.79 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0498

GRAVY Index0.20

Hydrophobic Moment 0.62

Boman Index0.20

Instability Index50.22

Aliphatic Index 106.00

Aromaticity 0.0857

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2882.80

LogP -18.12

H-bond Donors 94.0

H-bond Acceptors 98.0

Rotatable Bonds 241.0

Heavy Atoms 537.0

Ring Count 14.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191080 VERIFIED: NO

Provenance & Taxonomy

OrganismApis cerana [Animal]

FamilyMelittin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function