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MYP_006063
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Basic Information
Neuropeptide Y
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Neuropeptide Y family
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Reproductive biology ▸ Reproductive modulation
Standard
36 amino acids
C190H286N54O58
Standard
Sequence
YPSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY
Physicochemical Analysis
4254.63 Da
6.76
-0.15
-0.42
-0.0042
-1.14
0.73
-0.23
60.31
65.28
0.1389
7450.00
7450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1826.57
-17.24
63.0
59.0
131.0
302.0
10.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0221705 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
10-12 μM
MIC
PMID9756788 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9756788/
RECORD: Rec_0256714 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Neuropeptide Y
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation Feeding regulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuropeptide Y (Sus scrofa): PMID 6957876 PMID6957876 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6957876/
RECORD: Rec_0277955 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0282109 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Neuropeptide Y
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation Feeding regulator
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Neuropeptide Y (Bos taurus): PMID 15147401 PMID15147401 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15147401/
RECORD: Rec_0344259 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Porcine [other]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
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