Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC462H764N114O125S5

DescriptionStandard

        MKSKRMEFHNKFLIVSVMLAVISWLSLGVVSFPMLAGTLGISTGSAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYMLKKKSAAKAALW
    

Molecular Weight10076.02 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)6.58

Net Charge (pH 7.4) 6.30

Charge Density (pH 7.0) 0.0672

GRAVY Index1.02

Hydrophobic Moment 0.42

Boman Index0.40

Instability Index17.02

Aliphatic Index 124.39

Aromaticity 0.0714

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3750.07

LogP -32.23

H-bond Donors 136.0

H-bond Acceptors 138.0

Rotatable Bonds 334.0

Heavy Atoms 706.0

Ring Count 11.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0029965 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus sp. M334 [Bacterium]

FamilyBacteriocin

Tax ID563038

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal