Peptide Database

Peptide NameSLAY-screened peptide P2658

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC112H186N34O26S

DescriptionStandard

        PLRDITRRIWRGLLMKVADF
    

Molecular Weight2456.95 Da

Isoelectric Point (pI)11.54

Net Charge (pH 7.0)2.96

Net Charge (pH 7.4) 2.90

Charge Density (pH 7.0) 0.1480

GRAVY Index-0.07

Hydrophobic Moment 0.97

Boman Index-0.13

Instability Index31.27

Aliphatic Index 117.00

Aromaticity 0.1000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 986.47

LogP -5.20

H-bond Donors 38.0

H-bond Acceptors 30.0

Rotatable Bonds 82.0

Heavy Atoms 173.0

Ring Count 4.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0033392 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/