Peptide Database

Peptide NameRasburicase

Function Ontology

Anticancer

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length301 amino acids

Chemical FormulaC1521H2381N417O461S7

DescriptionStandard

        SAVKAARYGKDNVRVYKVHKDEKTGVQTVYEMTVCVLLEGEIETSYTKADNSVIVATDSIKNTIYITAKQNPVTPPELFGSILGTHFIEKYNHIHAAHVNIVCHRWTRMDIDGKPHPHSFIRDSEEKRNVQVDVVEGKGIDIKSSLSGLTVLKSTNSQFWGFLRDEYTTLKETWDRILSTDVDATWQWKNFSGLQEVRSHVPKFDATWATAREVTLKTFAEDNSASVQATMYKMAEQILARQQLIETVEYSLPNKHYFEIDLSWHKGLQNTGKNAEVFAPQSDPNGLIKCTVGRSSLKSKL
    

Molecular Weight34109.15 Da

Isoelectric Point (pI)7.16

Net Charge (pH 7.0)0.43

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) 0.0014

GRAVY Index-0.47

Hydrophobic Moment 0.76

Boman Index-0.04

Instability Index37.34

Aliphatic Index 80.60

Aromaticity 0.0897

Extinction Coeff. Reduced 53400.00

Extinction Coeff. Oxidized 53525.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029218 VERIFIED: YES

Provenance & Taxonomy

OrganismSaccharomyces cerevisiae [Fungus]; Aspergillus flavus [Fungus]

FamilyEnzyme

Tax ID4932; 5059

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Enzyme replacement

Half-Life18 hours

RECORD: Rec_0123171 VERIFIED: NO