Peptide Database

Peptide NameMu-conotoxin GVIIJ

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC155H239N43O50S7

DescriptionStandard

        GWCGDPGATCGKLRLYCCSGFCDCYTKTCKDKSSA
    

Molecular Weight3729.27 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)1.69

Net Charge (pH 7.4) 1.37

Charge Density (pH 7.0) 0.0482

GRAVY Index-0.31

Hydrophobic Moment 0.49

Boman Index-0.04

Instability Index17.62

Aliphatic Index 28.00

Aromaticity 0.1143

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1499.44

LogP -19.63

H-bond Donors 61.0

H-bond Acceptors 59.0

Rotatable Bonds 119.0

Heavy Atoms 255.0

Ring Count 6.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202274 VERIFIED: YES

Provenance & Taxonomy

OrganismConus geographus [Animal]

Tax ID6490; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-18; 10-22; 17-29

Other Mods2-W: 6'-bromotryptophan; 6-P: 4-hydroxyproline; 24-C: S-cysteinyl cysteine

Bio-Activity Profile

Function

Toxin Venom Ion channel inhibitor Pathogenesis-associated