Peptide Database

Peptide NameSLAY-screened peptide P808

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC97H164N28O31

DescriptionStandard

        VPPDTIVRDDSVALLTTLRH
    

Molecular Weight2218.51 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-1.18

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0588

GRAVY Index0.07

Hydrophobic Moment 0.36

Boman Index0.01

Instability Index42.12

Aliphatic Index 126.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 943.94

LogP -9.15

H-bond Donors 33.0

H-bond Acceptors 31.0

Rotatable Bonds 68.0

Heavy Atoms 156.0

Ring Count 3.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336263 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/