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MYP_005934
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Basic Information
Ponericin G5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
30 amino acids
C144H239N39O35S
Standard
Sequence
GLKDWVKIAGGWLKKKGPGILKAAMAAATQ
Physicochemical Analysis
3108.74 Da
10.30
4.76
4.54
0.1585
0.03
0.52
0.16
9.26
94.67
0.0667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1186.75
-7.78
41.0
41.0
106.0
219.0
5.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050230 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]; Insecta [Animal]
Ponericin
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0129804 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0254466 VERIFIED: NO
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0289021 VERIFIED: YES
Provenance & Taxonomy
Neoponera goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ. Biol. Chem. 2001; 276: 17823-17829. PubMed. | http://www.ncbi.nlm.nih.gov/pubmed/11279030 PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0303227 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
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