MYP_005919
Basic Information
mu-Conotoxin CIIIA
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
Standard
22 amino acids
C92H146N36O30S6
Standard
Sequence
GRCCEGPNGCSSRWCKDHARCC
Physicochemical Analysis
2428.76 Da
8.35
1.79
1.45
0.0814
-0.89
0.66
-0.34
46.26
4.55
0.0455
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1079.97
-16.61
45.0
39.0
77.0
164.0
4.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0235230 VERIFIED: YES
Provenance & Taxonomy
Conus catus [Animal]
Conotoxin
Structure & Mods
disulfide-constrained linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
3-15; 4-21; 10-22
Bio-Activity Profile
Toxin Ion channel inhibitor Sodium channel blocker
tetrodotoxin-resistant voltage-gated sodium channels in frog dorsal root ganglion neurons
voltage-clamp sodium-current inhibition assay
RECORD: Rec_0268823 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic
RECORD: Rec_0331458 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Miscellaneous