Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC510H817N135O142S7

DescriptionStandard

        MNLFLVTAILLIQNPTVTEQLKKCWGDYVQGHCRRICKVTEIRKALCENGRYCCLSISKLEERKKFTKPPPPKPQPFALTLPQDEVPEIFSTLETYHT
    

Molecular Weight11336.22 Da

Isoelectric Point (pI)8.80

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0370

GRAVY Index-0.33

Hydrophobic Moment 0.65

Boman Index-0.04

Instability Index46.77

Aliphatic Index 85.51

Aromaticity 0.0816

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4444.91

LogP -36.50

H-bond Donors 156.0

H-bond Acceptors 155.0

Rotatable Bonds 371.0

Heavy Atoms 794.0

Ring Count 20.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311792 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence