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MYP_005840
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Basic Information
TC-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Standard
68 amino acids
C320H551N95O97S5
Standard
Sequence
AELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAGDES
Physicochemical Analysis
7441.70 Da
9.05
3.94
3.57
0.0579
-0.32
0.60
-0.08
22.12
97.50
0.0000
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3119.35
-32.38
110.0
108.0
261.0
517.0
5.0
72.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0316979 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus neoformans
1.9 μM
MFC
PMID10877842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
RECORD: Rec_0321191 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumonia ATCC 700603
9.78 μg/mL
MIC
PMID30513368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30513368/
RECORD: Rec_0344456 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis
0.4 μM
MBC
PaperPubMed PMID: 10877842 | PubMed PMID: 8034022 PMID10877842;8034022 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
RECORD: Rec_0397047 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
PaperThrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines
RECORD: Rec_0405100 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
3.4 μM
MBC
PaperPubMed PMID: 10877842 | PubMed PMID: 8034022 PMID10877842;8034022 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10877842/
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