Peptide Database

Peptide NameTetrapeptide

Function Ontology

Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging

Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Collagen boosting

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC15H27N5O7

DescriptionStandard

        GEKG
    

Molecular Weight389.40 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0595

GRAVY Index-2.05

Hydrophobic Moment 0.59

Boman Index-0.32

Instability Index-32.58

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 213.94

LogP -2.89

H-bond Donors 7.0

H-bond Acceptors 7.0

Rotatable Bonds 14.0

Heavy Atoms 27.0

Ring Count 0.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088424 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTetrapeptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-aging Collagen boosting

TargetNormal human dermal fibroblasts (NHDF) (In vitro)

MethodCell viability assay; Cytotoxicity assay; ELISA; Immunohistochemistry; Wound healing assay; Clinical assessment

RECORD: Rec_0137543 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTetrapeptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-aging Collagen boosting

TargetHealthy human (>35 years of age) (Randomized clinical trial)

MethodCell viability assay; Cytotoxicity assay; ELISA; Immunohistochemistry; Wound healing assay; Clinical assessment

RECORD: Rec_0214822 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTetrapeptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-aging Collagen boosting

TargetPrimary human foreskin fibroblasts (In vitro)

MethodCell viability assay; Cytotoxicity assay; ELISA; Immunohistochemistry; Wound healing assay; Clinical assessment

RECORD: Rec_0407170 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyTetrapeptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-aging Collagen boosting

TargetHuman (Randomized clinical trial)

MethodCell viability assay; Cytotoxicity assay; ELISA; Immunohistochemistry; Wound healing assay; Clinical assessment