Peptide Database

Peptide NameSLAY-screened peptide P5708

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC81H128N32O27

DescriptionStandard

        AGRYSSGRYHSRGGESVR
    

Molecular Weight1982.08 Da

Isoelectric Point (pI)10.83

Net Charge (pH 7.0)2.88

Net Charge (pH 7.4) 2.64

Charge Density (pH 7.0) 0.1602

GRAVY Index-1.45

Hydrophobic Moment 0.66

Boman Index-0.44

Instability Index37.97

Aliphatic Index 21.67

Aromaticity 0.1111

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 992.98

LogP -15.41

H-bond Donors 39.0

H-bond Acceptors 31.0

Rotatable Bonds 65.0

Heavy Atoms 140.0

Ring Count 3.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138689 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/