Peptide Database

Peptide NameDermaseptin-H4 (Dermaseptin-like peptide 4) (DMS4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC350H571N93O113S5

DescriptionStandard

        MAFMKKSLFLVLFLGMVSLSICEEEKRENEDEAKQEDDEQSEMKRGLWSTIKNVGKEAAIAAGKAALGALGEQ
    

Molecular Weight8050.16 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-4.48

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0614

GRAVY Index-0.32

Hydrophobic Moment 0.64

Boman Index-0.02

Instability Index49.74

Aliphatic Index 83.01

Aromaticity 0.0548

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3365.30

LogP -31.47

H-bond Donors 115.0

H-bond Acceptors 114.0

Rotatable Bonds 289.0

Heavy Atoms 561.0

Ring Count 5.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336003 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus azureus [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Non-hemolytic

TargetNo Target Organism Found