Peptide Database

Peptide NameParathyroid hormone

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC414H672N122O128S2

DescriptionStandard

        SVSEIQFMHNLGKHLSSMERVEWLRKKLQDVHNFVALGAPIAHRDGSSQRPLKKEDNVLVESYQKSLGEADKADVDVLTKAKSQ
    

Molecular Weight9470.64 Da

Isoelectric Point (pI)8.04

Net Charge (pH 7.0)0.82

Net Charge (pH 7.4) 0.38

Charge Density (pH 7.0) 0.0098

GRAVY Index-0.64

Hydrophobic Moment 0.60

Boman Index-0.14

Instability Index39.95

Aliphatic Index 85.83

Aromaticity 0.0476

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4088.18

LogP -42.91

H-bond Donors 140.0

H-bond Acceptors 135.0

Rotatable Bonds 330.0

Heavy Atoms 666.0

Ring Count 11.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0107681 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyParathyroid hormone

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation ACE inhibitory

Targetosteoblastic cells

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0145616 VERIFIED: YES