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MYP_005676
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Basic Information
Ib-AMP3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
20 amino acids
C111H165N39O24S4
Standard
Sequence
QYRHRCCAWGPGRKYCKRWC
Physicochemical Analysis
2558.00 Da
9.79
5.80
5.49
0.2902
-1.38
0.53
-0.47
46.66
5.00
0.2000
13980.00
14230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1050.88
-9.00
44.0
35.0
79.0
178.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0320226 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Plant]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
6-16
50% inhibition concentration increased dramatically to the range of 100 to >200 ug/ml when the medium was supplemented with 1 mM CaCl2 and 50 mM KCl. The N-terminal glutamine is believed to be cyclized (i.e., pyroglutamate, XXQ). It contains two disulfide bonds (6-16 & 7-20). Updated 7/2021
Bio-Activity Profile
Antimicrobial Antifungal
ion IC50 6 ug/ml), B. cinerea (IC50 6 ug/m), C. sphaerospermum (IC50 3 ug/m), Fusarium culmorum (IC50 6 ug/m), P. digitatum (IC50 3 ug/m), T. viride (IC50 12 ug/m)
PaperA Novel Family of Small Cysteine-rich Antimicrobial Peptides from Seed of Impatiens balsamina Is Derived from a Single Precursor Protein
RECORD: Rec_0322720 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal
Verticillium alboatrum
6 μg/mL
IC50
PaperPubMed PMID: 9305910 PMID9305910 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9305910/
RECORD: Rec_0326686 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Plant]
Impatiens family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
6-16; 7-20
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Botrytis cinerea
6 μg/mL
IC50
PaperPubMed PMID 9305910 | PubMed PMID 9454588 PMID9305910;9454588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9305910/
RECORD: Rec_0330329 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal
Cladosporium sphaerospermum
3 μg/mL
IC50
PaperPubMed PMID: 9305910 PMID9305910 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9305910/
RECORD: Rec_0341751 VERIFIED: YES
Provenance & Taxonomy
Impatiens balsamina [Plant]
Impatiens family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
6-16; 7-20
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Trichoderma viride
12 μg/mL
IC50
PaperPubMed PMID 9305910 | PubMed PMID 9454588 PMID9305910;9454588 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9305910/
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