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MYP_005641
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Basic Information
Glucagon-like peptide 1(7-37)
Gastrointestinal bioactivity ▸ Gastrointestinal motility
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Metabolic ▸ Glucose metabolism ▸ Antidiabetic ▸ Anti-diabetic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
31 amino acids
C151H228N40O47
Standard
Sequence
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Physicochemical Analysis
3355.67 Da
5.53
-1.15
-1.41
-0.0370
-0.24
0.48
0.10
14.71
69.35
0.1290
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1408.40
-14.28
50.0
47.0
110.0
238.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0305508 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg30 Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2753890 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2753890/
RECORD: Rec_0313998 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glucagon
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg30 Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2753890 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2753890/
RECORD: Rec_0322095 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihyperglycemic Metabolic regulation
MS, ELISA
P700 plasma, in vitro; >345600 s
PaperDegradation and Stabilization of Peptide Hormones in Human Blood Specimens PMID26222180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26222180/
RECORD: Rec_0344360 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon-like peptide 1(7-37)
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
8:Phosphoserine; 11:Phosphoserine; 30:Arginine amide
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Feeding regulator
peripheral tissue
Experimental: 2.4±0.3 (for first phase) minute; /144 seconds; Mammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Glucagon-like peptide 1(7-37) (Homo sapiens): PMID 8839678 PMID8839678 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8839678/
RECORD: Rec_0355946 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihyperglycemic Metabolic regulation
MS
P800 whole blood, in vitro; 43200 s
PaperDegradation and Stabilization of Peptide Hormones in Human Blood Specimens PMID26222180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26222180/
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