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MYP_005641
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Basic Information
Glucagon-like peptide 1(7-37)
Gastrointestinal bioactivity ▸ Gastrointestinal motility
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Metabolic ▸ Glucose metabolism ▸ Antidiabetic ▸ Anti-diabetic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
31 amino acids
C151H228N40O47
Standard
Sequence
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
Physicochemical Analysis
3355.67 Da
5.53
-1.15
-1.41
-0.0370
-0.24
0.48
0.10
14.71
69.35
0.1290
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1408.40
-14.28
50.0
47.0
110.0
238.0
6.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010905 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
glucagon family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-Ser: Phosphoserine; 11-Ser: Phosphoserine; 30-Arg: Arginine amide
Bio-Activity Profile
Hormone glucagon family
PaperPDB 3IOL structural record; X-ray; 2.10 A; chain B; residues 1-31
RECORD: Rec_0019445 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
γ-Glu-palmitoyl residue at position 21
Bio-Activity Profile
Anti-diabetic
Subcutaneously injected in Humans, in vivo; 46800 s
PMID12145241 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12145241/
RECORD: Rec_0051516 VERIFIED: YES
Provenance & Taxonomy
Octodon degus [Animal]
Glucagon
10160
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg30 Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2753890 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2753890/
RECORD: Rec_0059698 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Gastrointestinal motility
Radioimmunoassay and HPLC
Intravenous injection to dogs plasma, in vitro; 144 s
PMID8839678 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8839678/
RECORD: Rec_0072667 VERIFIED: YES
Provenance & Taxonomy
Canis familiaris [Animal]
Glucagon
9615
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Arg30 Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2753890 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2753890/
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