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MYP_005639
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Basic Information
Latarcin-3a (5-17) [M5,13L; K10A; E11,14K; L16A; K17L]
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C72H130N18O15
Standard
Sequence
LAKKLAKYLKKAL
Physicochemical Analysis
1487.91 Da
10.30
4.75
4.54
0.3657
-0.02
0.77
-0.09
-3.83
143.08
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
562.85
-0.95
20.0
20.0
55.0
105.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0087155 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PMID36212827 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/36212827/
RECORD: Rec_0145611 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa KPC+ 003321199
>128 μg/mL
MIC
PaperFirst generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
RECORD: Rec_0191059 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Klebsiella pneumoniae ATCC 13883
32 μg/mL
MIC
PaperFirst generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
RECORD: Rec_0192782 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 7133623
>128 μg/mL
MIC
PaperFirst generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
RECORD: Rec_0217169 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
64 μg/mL
MIC
PaperFirst generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
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