Peptide Database

Peptide NameInsulin-like peptide INSL6 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC121H186N28O36S4

DescriptionStandard

        GFADKCCAIGCSKEELAVACLPFVDF
    

Molecular Weight2737.20 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-2.27

Net Charge (pH 7.4) -2.54

Charge Density (pH 7.0) -0.0874

GRAVY Index0.81

Hydrophobic Moment 0.27

Boman Index0.29

Instability Index46.07

Aliphatic Index 82.69

Aromaticity 0.1154

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1003.50

LogP -7.81

H-bond Donors 37.0

H-bond Acceptors 38.0

Rotatable Bonds 87.0

Heavy Atoms 189.0

Ring Count 4.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422140 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyInsulin-like peptide INSL6

Tax ID10116

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Growth regulation Development regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour