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MYP_005632
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Basic Information
Angiotensin I-converting enzyme inhibitor IV
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C31H57N9O7
Standard
Sequence
LRIPVA
Physicochemical Analysis
667.84 Da
9.75
0.76
0.56
0.1267
1.37
0.34
0.29
67.73
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
261.93
-0.64
9.0
8.0
19.0
47.0
1.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032577 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
ACE inhibitory peptide
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive Enzyme inhibitory Antioxidant
Angiotensin-converting enzyme
PaperPubMed PMID 28333109 | PubMed PMID 12903940 PMID28333109;12903940 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28333109/
RECORD: Rec_0043091 VERIFIED: NO
Provenance & Taxonomy
Spinacia oleracea [Plant]
ACE-inhibitory peptide
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Antioxidant
ACE
0.38 μM
IC50
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0072105 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
0.38 μM
IC50
RECORD: Rec_0155199 VERIFIED: YES
Provenance & Taxonomy
Spinacia oleracea [Plant]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Antioxidant ACE inhibitory
Angiotensin-converting enzyme
0.38 μM
IC50
RECORD: Rec_0177278 VERIFIED: NO
Provenance & Taxonomy
Spinacia oleracea [Plant]
ACE-inhibitory peptide
3562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
0 mmHg
SBP decrease
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
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