‹ ›
MYP_005615
← PREVIOUS NEXT → BACK
Basic Information
PN-CATH2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C139H253N41O36S2
Standard
Sequence
EGCNILCLLKRKVKAVKNVVKNVVKSVVG
Physicochemical Analysis
3138.88 Da
10.05
5.81
5.60
0.2004
0.44
0.74
0.02
36.58
137.24
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1282.94
-10.93
46.0
44.0
113.0
218.0
0.0
31.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0337863 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa CMCC 10104
100 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0341756 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0343370 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant Anti-inflammatory
C. perfringens ATCC 13124, Bacillus subtilis CMCC63501
11.9 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
RECORD: Rec_0350904 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse erythrocytes
7.5 % Hemolysis
Hemolysis
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0361456 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans 1
100 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
FIRST PREV 1 ... 4 5 6 7 8 NEXT LAST
Showing 5 records on this page · Page 6 of 8