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MYP_005615
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Basic Information
PN-CATH2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C139H253N41O36S2
Standard
Sequence
EGCNILCLLKRKVKAVKNVVKNVVKSVVG
Physicochemical Analysis
3138.88 Da
10.05
5.81
5.60
0.2004
0.44
0.74
0.02
36.58
137.24
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1282.94
-10.93
46.0
44.0
113.0
218.0
0.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0166545 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aeromonas sobria
100 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0179525 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Mouse skin melanoma B16-F10
30-40 % Killing
Killing
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0207146 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii
100 μg/mL
MIC
PMID33242568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33242568/
RECORD: Rec_0207405 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant Anti-inflammatory
V. parahaemolyticus
3 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
RECORD: Rec_0253009 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculata [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-7
Bio-Activity Profile
Antimicrobial Antioxidant Anti-inflammatory
active: Staphylococcus aureus CMCC26003
3 μM
MIC
PaperIdentification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities.
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