Peptide Database

Peptide NamePutative colicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length593 amino acids

Chemical FormulaC2973H4523N791O879S12

DescriptionStandard

        MGDIVYLRIIGEKQGDISSGCGTYASVGNRWQVGHEDEIFAFALTNAITSTGNGVNLQGLQFCKLIDKSSPLLSNAINQNERLFIEIDLYRINKSGRWERYYYIQLRNASLTAIHVNISDNNLLTECVTVDYDYILCKHLIANTEFDWLAFPAGYNSLFIPPKSPPASNLKPEPLPVVNLPLSSPAVNPVYAKSCLKVKGCTDAGTAEEPAENFGQVAIFAQPVVDDCCGYHHPEANVIGEPAEAQTMLLFPSSVLATQIWGKWSLSGVLSATRGSYIGALASALYIPSAGEGSARVPGRDEFWYEEELRQKALAGSTATTRVRFFWGTDIHSKPQVYGVHTGEGTPYENVRVANMLWNEERQRYEFTPAHDVDGPLITWTPENPEHGNVPGHTGNDRPPLDQPTILVTPIPDGTDTYTTPPFPVPDPKEFNDYILVFPAGSGIKPIYVYLKEDPRKLPGVVTGHGVPLSPGTRWLDMSVSNNGNGAPIPAHIADKLRGREFKTFDEFREALWLEVSKDSVLLAQFIKSNQNNVSQGYSPYVPEEGYYYGPNEIVKKFQIHHVVAIEHGGGVYDIDNFRIVTPRLHDEIHYRR
    

Molecular Weight65794.27 Da

Isoelectric Point (pI)5.37

Net Charge (pH 7.0)-18.01

Net Charge (pH 7.4) -19.36

Charge Density (pH 7.0) -0.0304

GRAVY Index-0.31

Hydrophobic Moment 0.58

Boman Index0.06

Instability Index39.55

Aliphatic Index 83.02

Aromaticity 0.1046

Extinction Coeff. Reduced 102220.00

Extinction Coeff. Oxidized 102720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390604 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli O83:H1 [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence