Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC526H863N141O155S14

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGSWYVKKCLNDVGICKKKCKPEELHVKNGWAMCGKQRDCCVPADKRANYPAFCVQTKTTRTSTVTATTATTTLMMTTASMSSMTPTPVSPTG
    

Molecular Weight12091.24 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.0767

GRAVY Index-0.00

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index28.63

Aliphatic Index 66.76

Aromaticity 0.0631

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4735.01

LogP -52.52

H-bond Donors 174.0

H-bond Acceptors 179.0

Rotatable Bonds 396.0

Heavy Atoms 836.0

Ring Count 16.0

Amide Bonds 116.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0127529 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence