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MYP_005552
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Basic Information
Temporin-PE
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C69H118N14O15
Standard
Sequence
FLPIVAKLLSGLL
Physicochemical Analysis
1383.76 Da
8.75
0.76
0.55
0.0584
1.97
0.44
0.65
10.98
210.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
0.67
15.0
16.0
44.0
98.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0249507 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anticancer Anti-Gram-negative
HMEC-1
58.62 μM
IC50
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0250506 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis
8.0 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0256986 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Staphylococcus aureus
2 μM
MIC
PaperIdentification and target-modifications of temporin-PE: A novel antimicrobial peptide in the defensive skin secretions of the edible frog, Pelophylax kl. esculentus.
RECORD: Rec_0264869 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
RECORD: Rec_0282619 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anticancer Anti-Gram-negative
Staphylococcus aureus
2 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
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