‹ ›
MYP_005552
← PREVIOUS NEXT → BACK
Basic Information
Temporin-PE
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C69H118N14O15
Standard
Sequence
FLPIVAKLLSGLL
Physicochemical Analysis
1383.76 Da
8.75
0.76
0.55
0.0584
1.97
0.44
0.65
10.98
210.00
0.0769
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
449.98
0.67
15.0
16.0
44.0
98.0
2.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0012723 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl. esculentus [Animal]
Temporins
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antimicrobial
NCI-H-157 (lung cancer)
34.56 μM
IC50
PaperIdentification and target-modifications of temporin-PE: A novel antimicrobial peptide in the defensive skin secretions of the edible frog, Pelophylax kl. esculentus | https://pubmed.ncbi.nlm.nih.gov/29191658/ PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0013427 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anticancer Anti-Gram-negative
Fungus: Candida albicans
4 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0043911 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anticancer Anti-Gram-negative
Methicillin-resistant Staphylococcus aureus
4 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0050454 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
2.0 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
RECORD: Rec_0084669 VERIFIED: YES
Provenance & Taxonomy
Pelophylax kl.esculentus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
16.0 μM
MIC
PMID29191658 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29191658/
1 2 3 ... 6 NEXT LAST
Showing 5 records on this page · Page 1 of 6