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MYP_005488
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Basic Information
Phylloseptin-Co
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C92H158N22O23S
Standard
Sequence
FLSMIPKIAGGIASLVKNL
Physicochemical Analysis
1972.44 Da
10.00
1.76
1.55
0.0925
1.16
0.54
0.44
4.00
148.95
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.92
-4.02
24.0
26.0
66.0
138.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0191816 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli
64.93 μM
MIC
RECORD: Rec_0227223 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli NCTC 10418
128 μg/mL
MIC
PMID27589802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27589802/
RECORD: Rec_0309536 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
16 μg/mL
MIC
PaperDiscovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis.
RECORD: Rec_0334467 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes (0% Hemolysis at 16 microg/ml
16 μg/mL
Hemolysis
PMID27589802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27589802/
RECORD: Rec_0425635 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans NCPF 1467
16 μg/mL
MIC
PMID27589802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27589802/
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