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MYP_005488
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Basic Information
Phylloseptin-Co
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C92H158N22O23S
Standard
Sequence
FLSMIPKIAGGIASLVKNL
Physicochemical Analysis
1972.44 Da
10.00
1.76
1.55
0.0925
1.16
0.54
0.44
4.00
148.95
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.92
-4.02
24.0
26.0
66.0
138.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033669 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli
128 μg/mL
MIC
PaperDiscovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis.
RECORD: Rec_0035092 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
4.06 μM
MIC
RECORD: Rec_0058026 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
8.12 μM
MIC
RECORD: Rec_0061906 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
8 μg/mL
MIC
PaperDiscovery of Novel Bacterial Cell-Penetrating Phylloseptins in Defensive Skin Secretions of the South American Hylid Frogs, Phyllomedusa duellmani and Phyllomedusa coelestis.
RECORD: Rec_0099302 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa coelestis [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
8 μg/mL
MIC
PMID27589802 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27589802/
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