Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length220 amino acids

Chemical FormulaC1128H1709N253O336S7

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPFIDLDLKGIVYPAGNYTDPPYVAAPFTIPDQSNSMLYLAFSEYFFQTFSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMAAEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTTNIAANTSIALNIFDQKLMGSLCLNRLQFSLSHSNVGFFEILLLENILSYILQTEVIPSANGK
    

Molecular Weight24414.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.14

Net Charge (pH 7.4) -16.48

Charge Density (pH 7.0) -0.0734

GRAVY Index0.36

Hydrophobic Moment 0.60

Boman Index0.27

Instability Index46.78

Aliphatic Index 102.45

Aromaticity 0.1364

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209174 VERIFIED: NO

Provenance & Taxonomy

OrganismBucorvus abyssinicus (Northern ground-hornbill) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria