Peptide Database

Peptide NameS17K

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC77H122N20O33

DescriptionStandard

        SEETKENEGFTVTAEGK
    

Molecular Weight1855.91 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-3.53

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.2075

GRAVY Index-1.39

Hydrophobic Moment 0.19

Boman Index-0.23

Instability Index29.93

Aliphatic Index 22.94

Aromaticity 0.0588

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 891.47

LogP -12.07

H-bond Donors 30.0

H-bond Acceptors 30.0

Rotatable Bonds 65.0

Heavy Atoms 130.0

Ring Count 1.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0323401 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Replication inhibition

TargetAdenovirus | Vero cells

Activity10 μg/mL

Method% inhibition

Half-LifeMammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h

PaperAntiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Sala A, Ardizzoni A, Ciociola T, Magliani W, Conti S, Blasi E, Cermelli C | Intervirology. 2018;61(4):166-173. | DOI:10.1159/000494354 | PMID:30654366 PMID30654366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30654366/

RECORD: Rec_0349063 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic

RECORD: Rec_0390152 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAurein

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetAdenovirus

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