Peptide Database

Peptide NameDefensin Cg-Defm (Cg-Def) (Mantle defensin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC302H488N84O85S11

DescriptionStandard

        MKVFVLLTLAVLLMVSADMAFAGFGCPGNQLKCNNHCKSISCRAGYCDAATLWLRCTCTDCNGKK
    

Molecular Weight7008.33 Da

Isoelectric Point (pI)8.71

Net Charge (pH 7.0)3.51

Net Charge (pH 7.4) 3.11

Charge Density (pH 7.0) 0.0539

GRAVY Index0.43

Hydrophobic Moment 0.44

Boman Index0.15

Instability Index29.91

Aliphatic Index 82.62

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2704.49

LogP -27.81

H-bond Donors 102.0

H-bond Acceptors 101.0

Rotatable Bonds 231.0

Heavy Atoms 482.0

Ring Count 8.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008206 VERIFIED: YES

Provenance & Taxonomy

OrganismCrassostrea gigas [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-positive Non-hemolytic

TargetM. maritypicum (Not characterize)

RECORD: Rec_0210531 VERIFIED: YES