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MYP_005391
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Basic Information
Kappa-actitoxin-Bcs3a
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
38 amino acids
C173H287N57O50S6
Standard
Sequence
ACIDRFPTGTCKHVKKGGSCKNSQKYRINCAKTCGLCH
Physicochemical Analysis
4157.87 Da
9.46
6.90
6.52
0.1817
-0.59
0.56
-0.19
37.19
43.68
0.0526
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1756.46
-23.18
68.0
65.0
141.0
286.0
5.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0135846 VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Potassium channel blocker Toxin
Kv1 voltage-gated potassium channels
electrophysiological concentration-response assay
PaperBiochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum PMID23466933
RECORD: Rec_0431508 VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Potassium channel blocker Toxin
rKv1.1 voltage-gated potassium channel
405±20.56 nM
IC50 (two-electrode voltage-clamp electrophysiology)
PaperBiochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum PMID23466933
RECORD: Rec_0431509 VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Potassium channel blocker Toxin
rKv1.2 voltage-gated potassium channel
0.03±0.006 nM
IC50 (two-electrode voltage-clamp electrophysiology)
PaperBiochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum PMID23466933
RECORD: Rec_0431510 VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Potassium channel blocker Toxin
hKv1.3 voltage-gated potassium channel
74.11±20.24 nM
IC50 (two-electrode voltage-clamp electrophysiology)
PaperBiochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum PMID23466933
RECORD: Rec_0431511 VERIFIED: YES
Provenance & Taxonomy
Bunodosoma caissarum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Potassium channel blocker Toxin
rKv1.6 voltage-gated potassium channel
1.31±0.20 nM
IC50 (two-electrode voltage-clamp electrophysiology)
PaperBiochemical and electrophysiological characterization of two sea anemone type 1 potassium toxins from a geographically distant population of Bunodosoma caissarum PMID23466933
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