Peptide Database

Peptide NameNodal/BMP2 chimera NB250

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length110 amino acids

Chemical FormulaC572H877N161O157S9

DescriptionStandard

        HHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVDNGRVLLDHHKDMIVEECGCL
    

Molecular Weight12809.65 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)2.31

Net Charge (pH 7.4) 1.62

Charge Density (pH 7.0) 0.0210

GRAVY Index-0.49

Hydrophobic Moment 0.53

Boman Index-0.04

Instability Index40.58

Aliphatic Index 77.00

Aromaticity 0.1000

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5066.41

LogP -42.92

H-bond Donors 178.0

H-bond Acceptors 175.0

Rotatable Bonds 410.0

Heavy Atoms 899.0

Ring Count 29.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0163901 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide10-76; 39-107; 43-109

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling Angiogenic