Peptide Database

Peptide NameColicin-E3 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length406 amino acids

Chemical FormulaC1972H3087N541O598S8

DescriptionStandard

        MAGNKDIPRVKNPPSGDGHRVTYRFMTAAELAERDARQQAYDDMLARQAAFERTLPVTSSKDEIPRAGCVFAKSCKLPDAIIDYANPSGMVPTDSLNDYGEVAWLGAREADDAGLLNLHTISANTLPLGIGNIALRATAISALPAIGAASATVLAGLVALFWTPSLGDSALYTEDQLRALKQARTRVRLRVEQQADGSLKGYAFYTGKNRDWEMVDVAQFDLRDSQQVADLGDGIELIWTPAVDGSDILGIPALEAAPQAPHIWVYPPTEAADSIIVNPVYPPEYKDFILVFPVGSGVKPVYIVVNVSGRKLPNPDHDYHSPPETEEITGFSGLKEVKKKTPKQGGGGLRSRWMDAKGRTIYEWDSLHGELEAYLASDGSHLGSFDHTTGEQIDPPKKKRSIKKYL
    

Molecular Weight44198.39 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-8.76

Net Charge (pH 7.4) -9.53

Charge Density (pH 7.0) -0.0216

GRAVY Index-0.33

Hydrophobic Moment 0.66

Boman Index0.02

Instability Index40.45

Aliphatic Index 84.66

Aromaticity 0.0788

Extinction Coeff. Reduced 60850.00

Extinction Coeff. Oxidized 60975.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0390043 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas frederiksbergensis [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal