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MYP_005371
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Basic Information
Peptide 5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C30H62N20O6
Standard
Sequence
RRRRR
Physicochemical Analysis
798.94 Da
12.00
4.76
4.56
0.9520
-4.50
0.62
-2.53
466.24
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
489.22
-6.35
21.0
11.0
29.0
56.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0342555 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octadecanoic acid (C18)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus LAC methicillin-resistant Staphylococcus aureus
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0367517 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octadecanoic acid (C18)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0367870 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Conjugation with TMR
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22465335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22465335/
RECORD: Rec_0388553 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibitor
Human cytomegalovirus (Furin); CHO
0.99 μM
Ki
PaperPolyarginines are potent furin inhibitors. | Cameron A, Appel J, Houghten RA, Lindberg I. | J Biol Chem. 2000 | PMID:10958789 PMID10958789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10958789/
RECORD: Rec_0424386 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octadecanoic acid (C18)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus LAC methicillin-resistant Staphylococcus aureus
32 μg/mL
MIC
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
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