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MYP_005371
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Basic Information
Peptide 5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C30H62N20O6
Standard
Sequence
RRRRR
Physicochemical Analysis
798.94 Da
12.00
4.76
4.56
0.9520
-4.50
0.62
-2.53
466.24
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
489.22
-6.35
21.0
11.0
29.0
56.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0089203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oligoarginine/Polycationic
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with aminohexanoic space; lowercase source residues at positions 1,2,3,4,5 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
Jurkat
Fluorescence-based uptake assay
PMID11087855 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087855/
RECORD: Rec_0090900 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Oligoarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluorescein with aminohexanoic space
Bio-Activity Profile
Cell-penetrating peptide
Jurkat
Fluorescence-based uptake assay
PMID11087855 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11087855/
RECORD: Rec_0098897 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23534410 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23534410/
RECORD: Rec_0110462 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octadecanoic acid (C18)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 19606
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
RECORD: Rec_0120717 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Octadecanoic acid (C18)
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli K12
32 μg/mL
MIC
PMID30588791 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30588791/
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