Peptide Database

Peptide NameKininogen-2

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC383H597N113O107S2

DescriptionStandard

        AERNVPQSEEKTEQFLRDLSEISRLQRVPTGFTPFRGKFHSQSLRGLSETKKFKAPYNIHWHCKPGLLCKNFN
    

Molecular Weight8560.66 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)6.05

Net Charge (pH 7.4) 5.66

Charge Density (pH 7.0) 0.0828

GRAVY Index-0.91

Hydrophobic Moment 0.83

Boman Index-0.21

Instability Index71.82

Aliphatic Index 58.77

Aromaticity 0.1096

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3598.29

LogP -36.80

H-bond Donors 126.0

H-bond Acceptors 118.0

Rotatable Bonds 286.0

Heavy Atoms 605.0

Ring Count 17.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0193413 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina variegata [Animal]

FamilyKininogen

Tax ID8348

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Receptor modulation

Targetvitro relaxation of rat arterial smooth muscle

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0201179 VERIFIED: YES