Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length470 amino acids

Chemical FormulaC2323H3753N591O646S18

DescriptionStandard

        RIMSPCCWLALVALIPVTLGTNPGVEVRLTQTGLDYGRQLGIAAIQQKLKSIKIPDISGTQHVSPIGKVQYTLSNMQIVKVGLPQSAVGLVPGTGITLSINNAFISLHGNWRVKYLKIIKDSGSFDLNVNGLTISITIAIKSDGTGRPAVSAVSCGASIASVSIKFHGGASWLYNLFTKFIEKALRSALQKQICPLVVDAVSDLNPYLKTLNVEAQVDKYAEIEYSMVSSPTVSKSSIDLSLKGEFYSIGKHQEPPFSPIAFSLPPQVNNMLYMGMSAFTANSAAFVYDKAGALSLYVTDDMIPQSSPLRLNTKTFGAFIPQLTKLFPGLMMKLLVKTVKTPIVTFKPNNVTIQATGTVTAYAIQPNATLSPLFVLNLVCGKDAMMKNYGVPNLILPHLHRMSFTLGTSYVGQFQVGTLDNILQIVLKVVVIPKLNVQLAKGYPLPSIGKMKLVKTQLQVLKVRDVLFTI
    

Molecular Weight50874.39 Da

Isoelectric Point (pI)9.68

Net Charge (pH 7.0)21.22

Net Charge (pH 7.4) 20.55

Charge Density (pH 7.0) 0.0452

GRAVY Index0.30

Hydrophobic Moment 0.83

Boman Index0.20

Instability Index29.89

Aliphatic Index 110.09

Aromaticity 0.0766

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 39100.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389964 VERIFIED: NO

Provenance & Taxonomy

OrganismAnabas testudineus (Climbing perch) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria