Peptide Database

Peptide NameEsculentin 2 HYba2 (E2/2)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC168H286N46O48S3

DescriptionStandard

        SILSLFKMGAKALGKTLIKQAGKAGAEYVACKATNQC
    

Molecular Weight3814.54 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.19

Charge Density (pH 7.0) 0.1199

GRAVY Index0.20

Hydrophobic Moment 0.60

Boman Index0.12

Instability Index18.34

Aliphatic Index 90.00

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1534.76

LogP -15.96

H-bond Donors 55.0

H-bond Acceptors 56.0

Rotatable Bonds 134.0

Heavy Atoms 265.0

Ring Count 2.0

Amide Bonds 39.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0398105 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBrevinin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis MTCC 14416

Activity12 μM

MethodMIC

RECORD: Rec_0416692 VERIFIED: YES