Peptide Database

Peptide NameSLAY-screened peptide P1720

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC103H157N31O27S

DescriptionStandard

        PPPVARHPCFKHVSVDSYRT
    

Molecular Weight2293.61 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)2.12

Net Charge (pH 7.4) 1.95

Charge Density (pH 7.0) 0.1061

GRAVY Index-0.66

Hydrophobic Moment 0.39

Boman Index-0.13

Instability Index28.95

Aliphatic Index 48.50

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 901.26

LogP -8.91

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 65.0

Heavy Atoms 162.0

Ring Count 8.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232736 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/